Professor Karen Faulds

Pure and Applied Chemistry

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Publications

Label-free visualisation of the antifungal polyene drug, nystatin in biological membranes using Raman microscopy
Tipping William J, Bilal Zainab, Wells Robert C, Brown Jason L, Graham Duncan, Faulds Karen
Analytical Chemistry (2026)
https://doi.org/10.1021/acs.analchem.5c07342
Visualisation of a Brutons tyrosine kinase inhibitor using fluorescence and Raman microscopy
Merchant Andrew S, Tipping William J, Graham Duncan, Faulds Karen
Analytical Chemistry (2026)
https://doi.org/10.1021/acs.analchem.5c04965
Development of a surface enhanced Raman scattering lateral flow immunoassay with prolonged reproducibility and stability over time
Sloan-Dennison Sian, Clark Benjamin, Scullion Kathleen M, Smillie Fiona, Laing Stacey, Fineran Paul, Mair Joanne, Rathmell Cicely, Bingemann Dieter, Faircloth Jonathan, Creasey David, Shand Neil, Weir Christopher J, Dear James W, Graham Duncan, Faulds (She/Her) Karen
Analyst (2026)
https://doi.org/10.1039/D6AN00053C
A SERRS-based lateral flow assay for sensitive detection of mitochondrial DNA in endometriosis screening
Rey Gomez Laura M, Alom Kazi Morshed, Nadalini Audrey, Hnit Su Su Thae, Clark Benjamin, Lyu Nana, Hirani Rena, Sloan-Dennison Sian, Laing Stacey, Rathmell Cicely, Creasey David, Bingemann Dieter, Faircloth Jonathan, Shand Neil, Graham Duncan, Faulds Karen, Wang Yuling
ACS Sensors Vol 11, pp. 2707–2720 (2026)
https://doi.org/10.1021/acssensors.5c04674
A chemical probe for prostate-specific membrane antigen for real-time Raman imaging of prostate cancer cells
Tipping William J, Powell Daniel J, Wells Robert C, Grant Emma K, Tomkinson Nicholas CO, Faulds Karen, Graham Duncan
ACS Sensors (2026)
https://doi.org/10.1021/acssensors.5c03746
Under the lens : using Raman spectroscopy as a unique system in biofilm analyses
Bilal Zainab, Tipping William, Brown Jason L, Faulds Karen
Critical Reviews in Microbiology Vol 52, pp. 283-301 (2026)
https://doi.org/10.1080/1040841x.2025.2555937

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Research Interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

Professional Activities

Enhancing Pharmaceutical Drying Monitoring Through Depth-Resolved Raman Spectroscopy: A novel Spatially Offset Raman Spectroscopy (SORS) probe for in-line process monitoring
Contributor
3/3/2026
Spatially resolved Raman spectroscopy for Pharmaceutical Drying process – a development of an advanced PAT tool for process sustainability and efficiency
Contributor
2/3/2026
Development of a Spatially Offset Raman Spectroscopy Probe for Monitoring Pharmaceutical Drying
Contributor
25/1/2024
Development of a Spatially Resolved Spectroscopy probe for In-line Monitoring of Pharmaceutical Drying
Contributor
21/3/2023
Seminar
Invited speaker
11/2022
SciX 2022
Invited speaker
10/2022

More professional activities

Projects

Deep Raman Imaging of Bacterial Biofilms (Dstl Contribution to Studentship)
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator)
28-Jan-2025 - 31-Jan-2029
Development of SERS-based Sensors for Oligonucleotide Drug Investigation
Graham, Duncan (Principal Investigator) Faulds, Karen (Co-investigator)
01-Jan-2025 - 30-Jan-2029
UDLA 2527 University of Strathclyde | Clark, Ross
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Clark, Ross (Research Co-investigator)
01-Jan-2025 - 01-Jan-2029
UDLA 2527 University of Strathclyde | Armstrong, Becca
Faulds, Karen (Principal Investigator) Graham, Duncan (Co-investigator) Armstrong, Becca (Research Co-investigator)
01-Jan-2025 - 01-Jan-2029
UDLA 2527 University of Strathclyde | Hendrie, Grant
Laing, Stacey (Principal Investigator) Faulds, Karen (Co-investigator) Hendrie, Grant (Research Co-investigator)
01-Jan-2025 - 01-Jan-2029
Fraunhofer access to the Raman facility
Faulds, Karen (Principal Investigator)
01-Jan-2025 - 31-Jan-2026

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Contact

Professor Karen Faulds
Pure and Applied Chemistry

Email: karen.faulds@strath.ac.uk
Tel: 548 2507